Research Division, Federal Institute of Drugs and Medical Devices (BfArM), Bonn, Germany. Institute of Pharmacology of Natural Products and Clinical Pharmacology, University of Ulm, Ulm, Germany. Clinical Pharmacy, Department of Pharmacy, Saarland University, Saarbrücken, Germany. Institute for Clinical Pharmacology, University Medical Center Göttingen, Georg-August University, Göttingen, Germany. Department of Internal Medicine I, University of Ulm, Ulm, Germany.